Levocetirizine Uses
Levocetirizine (brand name: Xyzal) is an antihistamine used to treat allergy symptoms and conditions like hives. This medication works by blocking the action of histamine, a substance your body makes during an allergic reaction.
Uses of Levocetirizine
Levocetirizine is primarily used to relieve symptoms of allergies, including:
- Watery eyes
- Runny nose
- Itching eyes and nose
- Sneezing
Additionally, Levocetirizine helps relieve itching and hives (urticaria). It works by blocking histamine, which your body releases during an allergic reaction. However, it does not prevent or treat serious allergic reactions, such as anaphylaxis.
If you have been prescribed epinephrine by your doctor for severe allergic reactions, it is important to carry your epinephrine injector with you at all times and not to use levocetirizine as a substitute.

How to Use Levocetirizine (Xyzal)
If you are using the over-the-counter version of this medication to self-treat, read and follow all the directions on the product package. If you are unsure about anything, consult your pharmacist. If your doctor has prescribed this medication, take it exactly as directed.
Levocetirizine is usually taken by mouth once daily in the evening, with or without food. For those using the liquid form, measure the dose carefully using a special measuring spoon or device. Avoid using a household spoon as it may not give you the correct dosage.
The dosage of levocetirizine depends on factors such as your age, medical condition, and how you respond to the treatment. Never increase your dose or take it more frequently than directed.
If your condition does not improve or worsens, or if you think you have a serious medical issue, get medical help immediately.
Side Effects of Levocetirizine
Like all medications, Levocetirizine may cause side effects. Some common side effects include:
- Drowsiness
- Tiredness
- Dry mouth
- Fever
- Cough, especially in children
If these side effects persist or worsen, contact your doctor or pharmacist immediately.
In some cases, Levocetirizine may cause more serious side effects. These include:
- Difficulty urinating
- Weakness
A severe allergic reaction to Levocetirizine is rare, but if you notice any symptoms such as rash, swelling (especially of the face, tongue, or throat), severe dizziness, or trouble breathing, seek emergency medical help immediately.
Remember, not everyone experiences serious side effects, and many people use this medication without any major issues. Always follow your doctor’s advice on how to use the medication.
Precautions Before Using Levocetirizine
Before taking Levocetirizine, tell your doctor or pharmacist if you have any known allergies, especially to cetirizine, hydroxyzine, or other antihistamines. This medication may contain inactive ingredients that can cause allergic reactions or other problems.
If you have a history of difficulty urinating, particularly due to an enlarged prostate, or have kidney disease, inform your doctor before using Levocetirizine.
This medication may make you feel drowsy. Avoid activities that require alertness, such as driving or operating machinery, until you are sure you can do them safely. Alcohol and marijuana (cannabis) can increase drowsiness, so avoid drinking alcohol while using this medication.
If you are using the liquid form of Levocetirizine, it may contain sugar or aspartame. Therefore, use caution if you have conditions such as diabetes or phenylketonuria (PKU) that require limiting or avoiding these substances.
Levocetirizine may be harmful during pregnancy, so always discuss the risks and benefits with your doctor before use. This drug also passes into breast milk, so talk to your doctor before breastfeeding.
Interactions With Other Medications
Drug interactions can affect how Levocetirizine works or increase your risk for serious side effects. This document does not include all possible drug interactions. Keep a list of all medications (including prescription, over-the-counter, and herbal products) you use and share it with your doctor and pharmacist.
Tell your doctor if you are taking other medications that may cause drowsiness, such as:
- Opioid pain relievers (e.g., codeine, hydrocodone)
- Drugs for sleep or anxiety (e.g., alprazolam, lorazepam)
- Muscle relaxants (e.g., carisoprodol, cyclobenzaprine)
- Other antihistamines (e.g., diphenhydramine, promethazine)
Be sure to check labels on other medications (such as those for allergies or cough and cold) as they may contain ingredients that also cause drowsiness.
Avoid using other antihistamines that are applied to the skin (e.g., diphenhydramine cream or ointment) while taking Levocetirizine due to the risk of increased side effects.
Overdose
If you or someone else has overdosed on Levocetirizine and is experiencing serious symptoms such as fainting or trouble breathing, call 911 immediately. For less severe symptoms, contact a poison control center right away.
In children, symptoms of overdose may include mental/mood changes such as restlessness or agitation before drowsiness sets in. For US residents, call 1-800-222-1222, and for Canada residents, call 1-844-764-7669.
Missed Dose
If you miss a dose of Levocetirizine, take it as soon as you remember, unless it is almost time for your next dose. In that case, skip the missed dose and resume your regular schedule. Do not double the dose to make up for a missed one.
Storage Instructions
Store Levocetirizine at room temperature, away from light and moisture. Do not store it in the bathroom. Keep all medications away from children and pets.
Do not flush medications down the toilet or pour them into a drain unless instructed to do so. Consult your pharmacist or local waste disposal company for proper disposal methods when the medication expires or is no longer needed.